Visual timeline of Bryan Johnson's daily routine from 4:30 AM wake-up through 8:30 PM sleep, showing the arc of his day including morning supplements, workout, meals before noon, work, and evening wind-down.

Routines

Bryan Johnson's Blueprint Protocol

By Noro Team Last updated 22 min read

Age Reversal Results

5.1 yrs Biological age reversed
0.48 DunedinPACE (ages at 48% rate)
64 > 36 Skin age reversal
#1 of 5,677 Rejuvenation Olympics
100% Sleep score (6+ months)
$2M/yr Personal protocol cost

New to this?

Start with 3 free things: go to bed at the same time every night, stop eating 3+ hours before sleep, and get morning light within 30 min of waking. Bryan says sleep is more impactful than any supplement. The DIY core protocol costs ~$165/month.

Monthly cost estimate

DIY core: ~$165/mo
Blueprint supplements: ~$361/mo
Full protocol: ~$1,685/mo
Sleep optimization and exercise are free. Bryan says: "Do less. Learn how to sleep."

Complete Stack

Full Supplement Protocol

100+ pills per day designed by 30+ doctors. Every supplement is data-driven and adjusted based on biomarker testing every 3-6 months.

Morning Stack Taken with pre-workout breakfast (~5:30 AM)

Blueprint Essential Capsules Core2 caps24 core nutrients: B vitamins, CoQ10, Fisetin, Luteolin, Lithium Orotate, D3, E, Zinc, Selenium, and more
NMN (Nicotinamide Mononucleotide) Core500 mgNAD+ precursor for cellular energy. Taken 6x/week.
NR (Nicotinamide Riboside) Core450 mgNAD+ precursor, alternating days with NMN. 6x/week.
Ca-AKG (Calcium Alpha-Ketoglutarate)1 g (x2/day)Mitochondrial health, metabolic support
Blueprint NAC + Ginger + Curcumin3 capsOxidative stress and inflammation
Blueprint Red Yeast Rice + Garlic1 capCholesterol and cardiovascular health
Ashwagandha600 mgStress adaptation, cortisol regulation
CoQ10 (Ubiquinol)100 mgCellular energy production
Vitamin D32,000 IUBone and immune health
EPA/DHA/DPA (Omega-3)800 mg (x2)Cardiovascular and brain health
Vitamin C500 mgAntioxidant, collagen synthesis (paired with collagen peptides)
BroccoMax (Sulforaphane)17.5 mgDetoxification, Nrf2 pathway activation
Fisetin200 mgSenolytic - clears senescent "zombie" cells
Spermidine10 mgAutophagy inducer
Lithium Orotate1 mgNeuroprotection, brain health (added 2026)
Lycopene10 mgAntioxidant
Garlic (whole)2.4 gCardiovascular support
Ginger Root2.2 gAnti-inflammatory
ProButyrate600 mgGut health, short-chain fatty acids
Plasmalogens (Glia + Neuro)1 mL eachBrain health

Midday Stack Taken with Super Veggie (~11 AM)

NAC (N-Acetyl-L-Cysteine)1,800 mgGlutathione precursor, liver detoxification
Cocoa Flavanols500 mgCirculation, brain health
Glucosamine Sulfate1,500 mgJoint health
L-Tyrosine500 mgDopamine production
Taurine1 gCardiovascular and brain support
Turmeric (Curcumin)1 gAnti-inflammatory
L-Lysine1 gProtein synthesis, amino acid support
Genistein125 mgPhytoestrogen, hormone balance
Viviscal1 pillHair growth support

Bedtime Stack Taken before 8:30 PM sleep

Melatonin (micro-dose)300 mcgSleep onset. Significantly lower than typical 3-10 mg OTC doses.
Taurine2 gCalming, cardiovascular (2nd dose)
Turmeric (Curcumin)1 gAnti-inflammatory (2nd dose)
NDGA50 mgAntioxidant, cellular longevity (added 2026)

Prescription Medications Under medical supervision

Metformin ER500-1,500 mgMetabolic health, longevity (6-week cycles)
Acarbose200 mg (2x)Blood sugar control with meals
Tadalafil (Cialis)2.5 mgEndothelial/vascular function
Candesartan8 mgBlood pressure regulation
Jardiance (Empagliflozin)10 mgMetabolic/cardiovascular longevity
Repatha (Evolocumab)140 mg / 2 wksLDL cholesterol reduction (injection)
Armour Thyroid + Levothyroxine60 mg / 100 mcgThyroid hormone optimization
Oral Minoxidil3.75 mgSystemic hair regrowth
Disclaimer: This is for informational purposes only. Bryan Johnson's protocol is experimental, combining on-label, off-label, and unlicensed therapies under the supervision of 30+ doctors. His biological age claims are preliminary and subject to biostatistical limitations. Consult a physician before starting any supplement or medication regimen.
4:30 AM - 9:00 AM

Morning

Data collection, 100+ pills, a 90-minute workout, sauna, and red light therapy. All before most people have their first coffee.

Wake Up + Data Check

Wakes naturally (no alarm) around 4:30-5:00 AM. Immediately checks inner ear temperature (~94°F vs normal 98.7°F), steps on Withings scale (weight, body fat, muscle mass, hydration, arterial stiffness), and reviews overnight wearable data from Whoop, Oura Ring, and Apple Watch.

Every decision in Bryan's day is made by data and algorithms, not personal preference. His mind is "unauthorized" to make health decisions.

Light Therapy + Breathwork

10,000 lux light therapy for 3-4 minutes directly into eyes (simulates sunrise since he wakes before dawn). Followed by a 5-minute breathing exercise and meditation to set a calm baseline for the day.

Hair Protocol

Blueprint Peptide Shampoo massaged with silicone brush for 60 seconds, rinsed after 2 minutes. Then 1 dropper of Blueprint Peptide Serum on dry scalp, followed by 6 minutes under a red light cap (655nm wavelength).

Full 7-step hair regrowth protocol

1. Topical 7% minoxidil (1 mL nightly). 2. Scalp massage with silicone scrubber (1-2 min). 3. Oral minoxidil (3.75 mg daily, prescription). 4. Blueprint Peptide Shampoo (daily). 5. Blueprint Peptide Serum (1 dropper daily). 6. Red light cap (655nm, 6 min daily). 7. Viviscal supplement (1 pill daily).

Pre-Workout Breakfast

Blueprint Longevity Protein with Blueberry Nut Mix (macadamia nuts, walnuts), 11g collagen peptides, 1 Tbsp extra virgin olive oil, and fresh berries. ~260 calories. Fuel for the workout without anything heavy.

Dry Sauna

175°F (93°C) for 20 minutes in a Plunge brand dry sauna. Uses an ice pack on his groin to prevent testicular heat damage. Rehydrates with 36 oz mineralized water after.

175°F Temperature
20 min Duration (daily)
Sauna results after 23 sessions

Central blood pressure decreased 12.6%. Central pulse pressure decreased 28.6%. Augmentation pressure decreased 50%. Resting heart rate decreased 4.4%. With ice protection (27 sessions): total motile sperm count increased 57%, sperm concentration increased 26%, motility increased 16%, morphology increased 15%.

Red Light + Shockwave Therapy

6 minutes of red/NIR light therapy via Celluma Pro panel (skin health) and full-body panels (3x/week, 12 min). Followed by shockwave therapy (3x/week, 4,500 shocks at intensity 14) targeting cervical spine, shoulders, ankles, elbows, hips, glutes, and knees.

Shower + Skincare + Oral Care

Complete Blueprint skincare routine (cleanser, serum, moisturizer with SPF). Oral care: Waterpik, floss, electric toothbrush, tongue scraper. His skin age reversed from 64 to 36 using this protocol combined with laser treatments every 6 months.

Key takeaway: Bryan's morning is a precision machine: data collection, 100+ pills, a full workout, sauna, and red light therapy. It's optimized by algorithms, not willpower.
9:00 AM - 12:00 PM

Midday

The two signature meals - Nutty Pudding and Super Veggie - plus the midday supplement stack. All eating is done by noon.

10:10 AM

10-Minute Outdoor Walk

Brief outdoor walk for natural light exposure and gentle movement. Transitions into focused work for the day.

Key takeaway: Two meals, both plant-based, both precisely measured. Nutty Pudding for brain health, Super Veggie for everything else. Every ingredient has a scientific purpose.
12:00 PM - 7:30 PM

Afternoon

Food stops at noon. The rest of the day is focused work, micro-movement every 30 minutes, and fluids cut off at 4 PM.

Third Meal (Final Food)

The last meal of the day. ~500 calories. Rotates between options like Stuffed Sweet Potato (sweet potato, chickpeas, avocado, grape tomatoes, radishes, cilantro, jalapeno, lime). Nothing else enters his body until tomorrow morning.

2,250 Total daily calories
17.5 hrs Daily fast (noon to 5:25 AM)
No food after noon. No fluids after 4 PM. No caffeine. No alcohol. No sugar. No seed oils. No processed food.
12:30 PM+

Focused Work + Micro-Movement

Work, projects, meetings until evening. Every 30 minutes, Bryan does 2-3 minutes of light activity: walking, bodyweight exercises, or stretching. Only mineralized water or tea allowed. All fluids stop at 4:00 PM to avoid sleep disruption.

Bryan Johnson"Blueprint is an algorithm that takes better care of me than I can myself."
Ongoing

Data Tracking

Continuous monitoring via Whoop (HRV, strain, recovery), Oura Ring (sleep stages, readiness, temperature), Apple Watch (heart rate, ECG, blood oxygen), and Continuous Glucose Monitor (real-time blood sugar response to food). His team of 30+ doctors reviews all data.

30+ Doctors on his team
3-6 mo Blood work frequency
2x/yr Epigenetic testing
Key takeaway: After noon, the body enters a 17.5-hour fast. No food, fluids stop at 4 PM. The afternoon is about work and letting digestion complete well before sleep.
7:30 PM - 8:30 PM

Evening

Sleep is Bryan's #1 priority. The evening is a precision wind-down designed for a 100% sleep score. He calls sleep "the most powerful drug on the planet."

Wind-Down Begins

10-minute outdoor walk, then transition to calming activities: reading a book, journaling, breathwork, meditation, bath, or calling a friend. Screens off 60 minutes before bed. All lights dimmed to warm/red tones 1-2 hours before bedtime.

Bryan Johnson"Every day starts the night before."

Evening Skincare + Oral Care

Face wash, apply skin serums, apply hair serums. Then topical minoxidil (7%, 1 mL) with 1-2 min scalp massage. Oral care: Waterpik, floss, electric toothbrush, tongue scraper, xylitol mouthwash. Insert SomnoDent bruxism device (stopped 20 years of teeth grinding).

Key takeaway: Bryan built his entire life around sleep. 8:30 PM bedtime, no exceptions. 100% sleep score for 6+ months. Everything else in the protocol is secondary to this.

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